Osmanlıspor Football Club was established on 21st of March, 1978 under the name of Ankara Belediyespor. Until 1994, the club operated in four different branches of sport. After the management change in 1994, new sport branches were added and the number of registered players exceeded 2000.

In 1984, the club was named Ankara Büyükşehir Belediyespor and 1998 its name was again changed to Büyükşehir Belediye Ankaraspor. As a result of decision of management in 2005, the football branch was removed from Ankara Büyükşehir Belediyesi and was privatised under the name of Ankaraspor A.Ş.

Before 2014-2015 season, Ankaraspor name was changed into Osmanlıspor Football Club and its colours were changed from blue-white to purple-yellow.

In 2013-2014 season, the club started to play in the first league under the name of Osmanlıspor FC. In 2014-2015 season, the club qualified for the Super League and had its best season ever. It collected 52 points and was ranked 5th in the league.  With this success, Osmanlıspor qualified to represent Turkey in UEFA Europa League Trophy in the second qualifying round of 2016-2017 season.

The Club yielded 5 wins and one draw in UEFA Europa League Qualification in 2016-2017 season and has qualified to represent Turkey in UEFA Europa league.